Periodontal Disease as the Initial Oral Manifestation of Langerhans Cell Histiocytosis - A Case Report


  • A R Ahmadi
  • S M Ismaij Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
  • Rosnah B Zain Department of Oral Pathology, Oral Medicine & Periodontology, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
  • Z Mohamad Zaini



langerhans cell histiocytosis, oral disease, manifestation


Langerhans Cell Histiocytosis (LCH) refers to a group of lesions presenting with a spectrum of clinical. features but sharing similar histology. These lesions are rare and treatment has been quite variable with current treatment protocol recommended being dependent on whether it is a unifocal or multi focal bone disease or a multi focal multisystem disease. However, the clinical presentations of LCH are variable and the decision to place into the appropriate clinical types may sometimes be masked by the non-discovery of all the lesions. In the oral maxillofacial area, the clinical features of these lesions may further pose a problem by nondescript manifestations as dental/periodontal/oral mucosal disorders. These oral findings may sometimes lead to inappropriate choice of treatment and delay in the diagnosis of all the lesions involved. This paper describes one such case where LCH manifest itself as a periodontal disease thus leading to delay in identifying all the sites involved and consequently a delay in id~ntifying the appropriate clinical type.


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Case Report