UTILITY OF AUTOFLUORESCENCE IMAGING IN THE DETECTION OF ORAL MUCOSAL LESIONS IN ELDERLY INSTITUTIONALISED SUBJECTS

Authors

  • Anand Ramanathan Department of Oro-Maxillofacial Surgical and Medical Science, Faculty of Dentistry, University of Malaya,
  • N A Rosedee Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Malaya
  • S A Edwer Department of Oro-Maxillofacial Surgical and Medical Science, Faculty of Dentistry, University of Malaya,
  • E P John Department of Diagnostic and Integrated Dental Practice, Faculty of Science, University of Malaya
  • K Palaniswany Primary Care Unit, Faculty of Dentistry, University of Malaya
  • Z A Bakar Primary Care Unit, Faculty of Dentistry, University Malaysia

Keywords:

Oral mucosal lesions, elderly institutionalised, conventional oral examination, autofluorescence imaging

Abstract

The prevalence of oral mucosal lesions in elderly population is 22.8% to 61.6%. Conventional oral examination (COE) is usually carried out to detect oral mucosal lesions (OML). However, new diagnostic aids have been introduced to improve OML detection. This study aimed to determine the utility of autofluorescence (AF) imaging in detecting OML from normal oral mucosa and its anatomic variation among institutionalised elderly Malaysian when compared with COE. Fifty subjects randomly selected from 9 nursing homes and COE and AF imaging using VELscope Vx, (LED Dental, Vancouver, British Columbia, Canada) were carried out. Sensitivity, specificity, positive (PPV) and negative predictive value (NPV) and accuracy of AF imaging were calculated. From the study, fifteen subjects had normal oral mucosa, 15 anatomic variations and 36 lesions were identified. The sensitivity and specificity of AF imaging were 100% and 70% whereas the PPV and NPV were 80% and 100% respectively. The accuracy of AF imaging was 86.37% when compared to COE. In conclusion AF imaging was able to detect OML and differentiate them from normal oral mucosa. However it has limited usefulness in differentiating between these lesions. This study however, was able to detail the AF imaging profile of normal oral mucosa, its normal variants and some common reactive or infective lesions which can be used in future OML studies as comparison to oral potentially malignant lesions.

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Published

2018-06-30

Issue

Section

Original/Research Article

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