ORAL SQUAMOUS CELL CARCINOMA WITH PSEUDO-GLANDULAR DIFFERENTIATION

Authors

  • Chan Siew Wui
  • F. K. Hartanto
  • L. Auzair
  • N. F. Mohd Tahir
  • N. Harun
  • L. O. Aung
  • C. H. Siar

Keywords:

Oral squamous cell carcinoma, pseudoglandular, adenoid, gland-like, histopathology, diagnosis

Abstract

Conventional oral squamous cell carcinomas are readily recognized histopathologically but the presence of additional atypical features may be challenging from a diagnostic point of view. We present a case of a welldifferentiated oral squamous cell carcinoma with pseudoglandular differentiation and discuss the possible differential diagnoses on a histopathological basis. Accurate diagnosis is imperative for timely and appropriate intervention and denotes distinctive prognostic implications. The presence of perivascular and perineural infiltrations as observed in this case would indicate the need for further post-operative therapeutic decision-making aimed at controlling local spread as well as distant metastases.

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Author Biography

Chan Siew Wui

Conventional oral squamous cell carcinomas are readily recognized histopathologically but the presence of additional atypical features may be challenging from a diagnostic point of view. We present a case of a welldifferentiated oral squamous cell carcinoma with pseudoglandular differentiation and discuss the possible differential diagnoses on a histopathological basis. Accurate diagnosis is imperative for timely and appropriate intervention and denotes distinctive prognostic implications. The presence of perivascular and perineural infiltrations as observed in this case would indicate the need for further post-operative therapeutic decision-making aimed at controlling local spread as well as distant metastases.

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Published

2018-06-29

Issue

Vol. 20 No. 2 (2013)

Section

Case Report

License

  1. The Faculty of Dentistry, Universiti Malaya holds the copyright of the published manuscript including all its components such as supplementary information, graphical contents and raw data without any restrictions.
  2. The author grant the Faculty of Dentistry, University of Malaya assignable and sub-licensable right, unlimited in time and territory, to copy-edit, reproduce, publish, distribute, transmit, make available and store the Article, including abstracts thereof, in all forms of media of expression now known or developed in the future, including pre- and reprints, translations, photographic reproductions and extensions.
  3. After acceptance for publication in Ann Dent UM, the author(s) have the right to use any of its components in whole or in part for academic purposes such as, presentation in scientific conferences and seminars.

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