Antibacterial Activity of Fine Chemicals from Scenedesmus acuminatus (Scenedesmaceae, Chlorococcales, Chlorophyta)
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Apr 26, 2007
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Abstract
Microalgae, Scenedesmus acuminatus was batch-cultured in a photo-bioreactor to facilitate better culture control and higher productivity. Each batch was cultured for 100 hours; final cell density and specific growth rate were 5.0 x 10â· cell / ml and 0.028 hourâ»Â¹, respectively. The harvested biomass produced 70.80 mg crude extract with antibacterial activities. Bioassay guided separation and spectroscopy data revealed a mixture offatty acid methyl esters (FAME) (C16:0, C16:1, C18:1n9c, C18:2n6c and C20:0) as the active principal. Further antibacterial bioassay with commercially available individual FAME revealed C18:1n9c methyl ester and C18:2n6c methyl ester, as the active compounds in the mixture. The active methyl esters, C18:1n9c and C18:2n6c, inhibited 48% (MIC: 0.3 µgdiscâ»Â¹) and 100% (MIC: 0.3 and 1.0 µgdiscâ»Â¹) of tested bacteria, respectively
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C.S, V., P.N, G., & M.Y, A. (2007). Antibacterial Activity of Fine Chemicals from Scenedesmus acuminatus (Scenedesmaceae, Chlorococcales, Chlorophyta). Malaysian Journal of Science, 26(1), 65–72. Retrieved from http://adum.um.edu.my/index.php/MJS/article/view/7974
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